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Lymphocyte activation can occur in several ways. However, in all cases


A) lymphocytes must recognize an antigen.
B) helper T cells are activated first and they then stimulate other cells.
C) antigen-presenting cells process the antigen and present it to the lymphocytes.
D) cytokines released by the antigen stimulate the lymphocyte response.
E) antigens must be able to recognize the lymphocytes.

F) A) and C)
G) A) and B)

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A

Lymphocyte proliferation begins by increasing the number of


A) macrophages.
B) B cells.
C) T suppressor cells.
D) helper T cells.
E) cytotoxic T cells.

F) B) and D)
G) C) and D)

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Antibodies


A) play a large role in cell-mediated immunity.
B) are produced by both T and B cells.
C) are composed of four light and four heavy polypeptide chains.
D) are not specific, but act generally.
E) have a variable region that binds to a specific antigenic determinant.

F) A) and E)
G) A) and C)

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Match the term or description to the type of hypersensitivity. -anaphylaxis


A) immediate hypersensitivity
B) delayed hypersensitivity

C) A) and B)
D) undefined

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Which of the following cytokines is mismatched?


A) perforin - makes a hole in target cell membranes
B) alpha interferon - prevents viral replication
C) lymphotoxin - costimulator of T cells
D) interleukin 4 - plays a role in allergic reactions
E) TNF - activates macrophages and promotes fever

F) A) and D)
G) B) and E)

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C

  -What does  A  represent on the diagram? A)  spleen B)  thymus C)  axillary lymph node D)  inguinal lymph node E)  thoracic duct -What does "A" represent on the diagram?


A) spleen
B) thymus
C) axillary lymph node
D) inguinal lymph node
E) thoracic duct

F) C) and D)
G) A) and B)

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Match the appropriate characteristic with the type of immunity. -origin of cells is red bone marrow


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity, antibody-mediated immunity and cell-mediated immunity

F) C) and D)
G) B) and E)

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  -The diagram illustrates the stimulation and effects of T cells. What does  A  represent? A)  memory T cells B)  cytotoxic T cells C)  contact killing D)  lysis of target cell E)  release of cytokines -The diagram illustrates the stimulation and effects of T cells. What does "A" represent?


A) memory T cells
B) cytotoxic T cells
C) contact killing
D) lysis of target cell
E) release of cytokines

F) A) and B)
G) B) and D)

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B

____ are part of cell-mediated immunity while ____ are part of antibody-mediated immunity.


A) B cells, NK cells
B) Antibodies, antigens
C) T cells, B cells
D) Macrophages, antibodies
E) Neutrophils, monocytes

F) A) and B)
G) B) and C)

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What is the purpose of lacteals?


A) Drain blood from the spleen.
B) Absorb fluid from capillary beds.
C) Absorb lipids from the digestive tract.
D) Absorb solutes from interstitial spaces.

E) A) and B)
F) A) and C)

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Match the appropriate characteristic with the type of immunity. -cells that provide this immunity are lymphocytes.


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity, antibody-mediated immunity and cell-mediated immunity

F) A) and E)
G) A) and D)

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Match the type of cell with its function. -natural killer cell


A) first cell to enter infected tissue
B) will become macrophage in tissue
C) lyses tumor and virus-infected cells
D) cell that increases in number during a parasitic infection
E) nonmotile cells in connective tissue that promote inflammation

F) All of the above
G) D) and E)

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  -What does  B  represent on the diagram? A)  spleen B)  thymus C)  axillary lymph node D)  inguinal lymph node E)  thoracic duct -What does "B" represent on the diagram?


A) spleen
B) thymus
C) axillary lymph node
D) inguinal lymph node
E) thoracic duct

F) A) and E)
G) A) and D)

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The two major types of phagocytic cells are


A) neutrophils and monocytes.
B) neutrophils and macrophages.
C) monocytes and macrophages.
D) lymphocytes and monocytes.
E) eosinophils and T cells.

F) C) and E)
G) A) and B)

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The palatine tonsils


A) interfere with breathing when enlarged.
B) are located at the junction of the oral cavity and pharynx.
C) are located superior to the palate.
D) are really lymph nodes in disguise.
E) are located in the nasopharynx.

F) B) and E)
G) None of the above

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Frequently, several different signals or molecules are needed in order to produce an immune response by a B cell or T cell. The second signal in this process is called


A) opsonization.
B) copresentation.
C) complement activation.
D) antigen processing.
E) costimulation.

F) C) and D)
G) B) and C)

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Cytotoxic T cells


A) produce antibodies for general circulation.
B) attach to the surface of cells causing them to lyse.
C) cause precipitation of antigens.
D) have IgG antibodies on their cell membranes.
E) are destroyed after contact killing.

F) A) and B)
G) A) and C)

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  -This diagram illustrates the effects of antibodies. What effect does  D  represent? A)  activation of complement cascade B)  facilitation of phagocytosis C)  initiates release of inflammatory chemicals D)  binds antigens together E)  inactivation of antigens -This diagram illustrates the effects of antibodies. What effect does "D" represent?


A) activation of complement cascade
B) facilitation of phagocytosis
C) initiates release of inflammatory chemicals
D) binds antigens together
E) inactivation of antigens

F) A) and D)
G) C) and D)

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  -This diagram illustrates the effects of antibodies. What effect does  B  represent? A)  activation of complement cascade B)  facilitation of phagocytosis C)  initiates release of inflammatory chemicals D)  binds antigens together E)  inactivation of antigens -This diagram illustrates the effects of antibodies. What effect does "B" represent?


A) activation of complement cascade
B) facilitation of phagocytosis
C) initiates release of inflammatory chemicals
D) binds antigens together
E) inactivation of antigens

F) C) and D)
G) All of the above

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Which of the following is NOT an aging effect of the lymphatic system and immunity?


A) Fluid removal by the lymphatic capillaries is reduced.
B) Fewer antibodies are produced.
C) Onset of autoimmune diseases is unchanged.
D) T cell numbers remain constant but they are less functional.

E) A) and B)
F) B) and C)

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