Question 1

T cell receptors are identical to antibodies.

Accepted Answer

A) True 
 B)False

Question 2

Which of the following antibodies is a dimer?

Accepted Answer

A)   IgD
B)   IgA
C)   IgM
D)   IgE
E)   IgGF) B) and E)
G) C) and D)

Question 3

How is the central portion of a T cell receptor complex functionally analogous to the center of the B cell receptor complex?

Accepted Answer

A)   It has two protein chains, just like a B-cell receptor.
B)   Both receptors bind epitopes (small amino acid sections of antigen molecules) .
C)   Both bind structures directly on the surface of microbes.
D)   Both can be secreted from lymphocytes to bind to pathogens under certain situations.
E)   Both have two heavy chains and two light chains.F) C) and D)
G) A) and B)

Question 4

What is a naive lymphocyte?

Accepted Answer

A)   A lymphocyte that has an antigen receptor but has not yet encountered the antigen recognized by the receptor.
B)   A lymphocyte that has encountered the antigen recognized by its receptor but has not yet made antibodies.
C)   A lymphocyte that has encountered the antigen recognized by its receptor but has not yet made antibodies and cytokines.
D)   A lymphocyte that has encountered the antigen recognized by its receptor but has not yet undergone apoptosis.
E)   A lymphocyte that has not yet encountered the antigen recognized by its receptor but is making antibodies.F) A) and E)
G) None of the above

Question 5

The chains of an antibody molecule are bonded to one another by

Accepted Answer

A)   disulfide bonds.
B)   hydrogen bonds.
C)   ionic bonds.
D)   oxygen bonds.
E)   ligases.F) All of the above
G) D) and E)

Question 6

A fetus is protected by maternal antibodies that cross the placenta. You explain to Ellie that the fetus

Accepted Answer

A)   is protected by both maternal IgG and maternal IgM, because these can easily cross the placenta.
B)   is protected by maternal IgM but not by maternal IgG, because IgM can cross the placenta but IgG cannot because it is a pentamer.
C)   will make large amounts of its own IgG and IgM immediately if the mother contracts some type of pathogen.
D)   is protected by maternal IgG but not by maternal IgM-IgG can cross the placenta but IgM cannot because it is a pentamer.
E)   will make its own IgG if the mother contracts any type of pathogen; it cannot make IgM because this is a pentamer.F) B) and E)
G) A) and B)

Question 7

Which of the following class of antibody is primarily found in external secretions?

Accepted Answer

A)   IgA
B)   IgD
C)   IgG
D)   IgE
E)   IgMF) A) and B)
G) D) and E)

Question 8

Which of the following do not induce a strong immune response?

Accepted Answer

A)   Lipids
B)   Proteins
C)   Polysaccharides
D)   Simple sugars
E)   Lipids AND simple sugars.F) C) and D)
G) B) and E)

Question 9

You inform your patient that the human body has several mechanisms of defense: innate immunity, which is routine protection present at birth, and adaptive immunity, which is a more specific response that develops after birth. You tell your patient that her adaptive immune response uses two basic strategies for eliminating foreign material: humoral immunity, which involves ________ and cell-mediated immunity, which involves ________.

Accepted Answer

A)   T lymphocytes; B lymphocytes
B)   B lymphocytes; T lymphocytes
C)   T lymphocytes; NK cells
D)   B cells; neutrophils
E)   neutrophils; macrophagesF) B) and D)
G) All of the above

Question 10

T cells mature in the

Accepted Answer

A)   bone marrow.
B)   thymus.
C)   Peyer's patches.
D)   nervous tissue.
E)   tonsils.F) C) and D)
G) A) and B)

Question 11

You describe for your patient the sequence of events that occurs when a B cell is activated. Please select the correct order of statements.
1)  TH cells recognize the presented antigen-MHC complex on the B cell and bind to it.
2)  B cell receptor binds to an antigen and the antigen is internalized by endocytosis.
3)  The bound TH delivers cytokines to the B cell that initiate the process of clonal expansion of that particular B cell.
4)  The antigen is degraded and peptide fragments are expressed at the B cell membrane with MHC class II molecules.

Accepted Answer

A)   1, 2, 3, 4
B)   4, 3, 1, 2
C)   1, 3, 2, 4
D)   2, 3, 1, 4
E)   2, 4, 1, 3F) C) and D)
G) A) and D)

Question 12

Cytotoxic T cells primarily are responsible for

Accepted Answer

A)   humoral immunity.
B)   cell-mediated immunity.
C)   anamnestic immunity.
D)   producing haptens.
E)   producing antibodies.F) A) and C)
G) All of the above

Question 13

Which of the following does NOT form a memory population after activation and differentiation?

Accepted Answer

A)   B cells.
B)   T cytotoxic cells.
C)   T helper cells.
D)   Macrophages.
E)   These all form memory cells.F) All of the above
G) B) and C)

Question 14

T-independent antigens

Accepted Answer

A)   include polysaccharides.
B)   require the involvement of T cells.
C)   interact with MHCI molecules.
D)   are usually proteins.
E)   include polysaccharides AND require the involvement of T cells.F) A) and D)
G) D) and E)

Question 15

Your friend asks you how her B cells "know" when to make antibodies. You tell her that B cells must become activated, and that she has another type of cell that assists in this. These are the

Accepted Answer

A)   TH cells that bind to the B cell and release cytokines that activate that B cell.
B)   TC cells that bind to the B cell and release cytokines that activate that B cell.
C)   TH cells that bind to the B cell and release cytokines that activate that T cell.
D)   TC cells that bind to the B cell and release cytokines that activate that T cell.
E)   TH cells that present the antigen to the B cell, leading to activation of that B cell.F) A) and D)
G) B) and D)

Question 16

A term synonymous with antibody is

Accepted Answer

A)   antigen.
B)   immunoglobulin.
C)   epitope.
D)   determinant.
E)   immunotope.F) A) and E)
G) A) and D)

Question 17

Antigens may be processed for presentation by

Accepted Answer

A)   macrophages AND erythrocytes.
B)   dendritic cells AND erythrocytes.
C)   erythrocytes, macrophages, AND dendritic cells.
D)   T cytotoxic cells, B cells, AND dendritic cells.
E)   macrophages, B cells, AND dendritic cells.F) C) and E)
G) A) and B)

Question 18

Antigens interact with antibodies at

Accepted Answer

A)   the outer end of each arm of the Y.
B)   the junction of heavy and light chains.
C)   different regions depending on the class of antibody.
D)   the bottom stem of the heavy chain of the Y.
E)   the disulfide bridges of the antibody molecule.F) A) and B)
G) A) and E)

Question 19

Which of the following is not typical of an antigen?

Accepted Answer

A)   Protein
B)   Foreign
C)   Low molecular weight
D)   Polysaccharide
E)   Low molecular weight AND proteinF) B) and C)
G) C) and D)

Question 20

Which of the following is/are secondary lymphoid organ(s) ?

Accepted Answer

A)   Thymus AND spleen
B)   Spleen AND lymph nodes
C)   Lymph nodes AND bone marrow
D)   Spleen AND bone marrow
E)   Thymus AND bone marrowF) C) and D)
G) A) and E)

Exam 15: The Adaptive Immune Response

Which of the following class of antibody is primarily found in external secretions?

Correct Answer
verified

A fetus is protected by maternal antibodies that cross the placenta. You explain to Ellie that the fetus

Correct Answer
verified

T cell receptors are identical to antibodies.

Correct Answer
verified

Which of the following do not induce a strong immune response?

Correct Answer
verified

The chains of an antibody molecule are bonded to one another by

Correct Answer
verified

Which of the following antibodies is a dimer?

Correct Answer
verified

T cells mature in the

Correct Answer
verified

What is a naive lymphocyte?

Correct Answer
verified

Correct Answer
verified

Which of the following is/are secondary lymphoid organ(s) ?

Correct Answer
verified

A term synonymous with antibody is

Correct Answer
verified

Cytotoxic T cells primarily are responsible for

Correct Answer
verified

Antigens interact with antibodies at

Correct Answer
verified

Antigens may be processed for presentation by

Correct Answer
verified

Your friend asks you how her B cells "know" when to make antibodies. You tell her that B cells must become activated, and that she has another type of cell that assists in this. These are the

Correct Answer
verified

How is the central portion of a T cell receptor complex functionally analogous to the center of the B cell receptor complex?

Correct Answer
verified

T-independent antigens

Correct Answer
verified

Which of the following is not typical of an antigen?

Correct Answer
verified

Correct Answer
verified

Which of the following does NOT form a memory population after activation and differentiation?

Correct Answer
verified

Exam 15: The Adaptive Immune Response

Which of the following class of antibody is primarily found in external secretions?

Correct AnswerverifiedShow Answer

A fetus is protected by maternal antibodies that cross the placenta. You explain to Ellie that the fetus

Correct AnswerverifiedShow Answer

T cell receptors are identical to antibodies.

Correct AnswerverifiedShow Answer

Which of the following do not induce a strong immune response?

Correct AnswerverifiedShow Answer

The chains of an antibody molecule are bonded to one another by

Correct AnswerverifiedShow Answer

Which of the following antibodies is a dimer?

Correct AnswerverifiedShow Answer

T cells mature in the

Correct AnswerverifiedShow Answer

What is a naive lymphocyte?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which of the following is/are secondary lymphoid organ(s) ?

Correct AnswerverifiedShow Answer

A term synonymous with antibody is

Correct AnswerverifiedShow Answer

Cytotoxic T cells primarily are responsible for

Correct AnswerverifiedShow Answer

Antigens interact with antibodies at

Correct AnswerverifiedShow Answer

Antigens may be processed for presentation by

Correct AnswerverifiedShow Answer

Your friend asks you how her B cells "know" when to make antibodies. You tell her that B cells must become activated, and that she has another type of cell that assists in this. These are the

Correct AnswerverifiedShow Answer

How is the central portion of a T cell receptor complex functionally analogous to the center of the B cell receptor complex?

Correct AnswerverifiedShow Answer

T-independent antigens

Correct AnswerverifiedShow Answer

Which of the following is not typical of an antigen?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Which of the following does NOT form a memory population after activation and differentiation?

Correct AnswerverifiedShow Answer

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