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How does the organization of the bacterial genome differ from the organization of the eukaryotic genome?


A) The compaction of the eukaryotic genome involves structural maintenance of chromosome (SMC) proteins, and the compaction of the bacterial genome does not.
B) Most bacterial chromosomes are circular and the eukaryotic chromosomes contained in the nucleus are not.
C) Bacterial chromosomes are made up of RNA and eukaryotic chromosomes are made up of DNA.
D) The eukaryotic genome is found on chromosomes and there are no chromosomes in bacterial cells.

E) A) and C)
F) None of the above

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The portion of the cell cycle when the cell is growing and does not contain a replicated genome is referred to as:


A) G1
B) S
C) G2
D) Mitosis

E) C) and D)
F) A) and D)

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A somatic cell from a garden pea normally contains 14 chromosomes.How many sister chromatids would that cell contain during G1 of the cell cycle?


A) 0
B) 7
C) 14
D) 28

E) None of the above
F) All of the above

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This is the stage of mitosis characterized by the alignment of the chromosomes in a ring along the inner circumference of the cell:


A) Interphase
B) Telophase
C) Prophase
D) Metaphase

E) C) and D)
F) B) and D)

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D

In bacterial cell division, the cell divides into two nearly equal halves.This process is referred to as:


A) binary fission
B) mitosis
C) fusion
D) meiosis

E) B) and C)
F) All of the above

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If a cell contained a mutation in the gene that encodes FtsZ, which process would be affected?


A) Septation
B) Cytokinesis
C) Prophase
D) DNA Synthesis

E) All of the above
F) A) and D)

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What is the sequence of events in a typical eukaryotic cell cycle?


A) G1 to G2 to S to mitosis to cytokinesis
B) G1 to S to G2 to mitosis to cytokinesis
C) G1 to S to G2 to cytokinesis to mitosis
D) G1 to G2 to mitosis to S to cytokinesis

E) B) and C)
F) A) and C)

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B

A person whose cells all contain a chromosome number of 2n+1 most likely has what type of condition?


A) Monosomy
B) Trisomy
C) Cancer
D) Obesity

E) C) and D)
F) B) and D)

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During this stage of mitosis, the chromosomes become attached to the spindle at their kinetochores.


A) Prophase
B) Prometaphase
C) Metaphase
D) Anaphase

E) A) and B)
F) C) and D)

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This protein or protein complex functions in the cell to stop cell division if the cell has experienced extensive DNA damage:


A) APC/C
B) p53
C) FtsZ
D) Condensin

E) A) and B)
F) A) and C)

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A scientist wants to study histones.Histones are:


A) proteins that double-stranded DNA molecules wrap around in eukaryotes.
B) proteins that double-stranded DNA molecules wrap around in prokaryotes and eukaryotes.
C) proteins that regulate checkpoints in the mitotic cell cycle.
D) proteins that serve as the spindle fiber to pull sister chromatids apart during anaphase.

E) A) and B)
F) A) and C)

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Eukaryotic chromosomes are composed of a complex of 60% protein and 40% DNA.This complex is referred to as:


A) The histone complex
B) Chromatin
C) The kinetochore
D) Cohesin

E) None of the above
F) B) and D)

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What happens during Anaphase B?


A) Kinetochores are pulled toward the poles.
B) The spindle poles move apart.
C) The spindle apparatus disassembles.
D) The nuclear envelope reforms.

E) All of the above
F) None of the above

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You are studying cell cycle progression in an early frog embryo.If you were to inject a protein synthesis inhibitor into a cell during S phase, where do you predict that the cells would arrest?


A) G1
B) G2
C) Metaphase
D) Telophase

E) None of the above
F) B) and D)

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A cell biologist produces a karyotype of mouse somatic cells arrested in mitosis.She sees 40 chromosomes, which is completely normal for mice.Based on this information, what is the haploid number of chromosomes for mice?


A) 10
B) 20
C) 40
D) 80

E) None of the above
F) B) and C)

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The stage of mitosis characterized by the physical separation of sister chromatids is called:


A) Anaphase
B) Metaphase
C) Prometaphase
D) Telophase

E) A) and B)
F) B) and C)

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A

You are studying cell cycle progression in yeast cells.If you could prevent cdc2 from associating with the mitotic cyclin, the cells would:


A) arrest in G1.
B) arrest in G2.
C) arrest in S.
D) arrest in prometaphase.

E) A) and B)
F) All of the above

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Animal cells typically achieve cytokinesis by:


A) binary fission.
B) forming a cell plate across the middle of the cell.
C) forming a cleavage furrow that pinches the cell into two.
D) chromosome condensation.

E) A) and D)
F) All of the above

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What would you expect to happen if the anaphase-promoting complex/cyclosome (APC/C) failed to ubiquitinate securin?


A) The cohesin complex will be destroyed, and the cell will remain in metaphase.
B) The cohesin complex will persist, preventing the cell from entering anaphase.
C) Separase will be marked for degradation by securin, preventing the cell from entering anaphase.
D) Securin will remain intact and therefore will degrade cohesin, allowing the cell to enter anaphase.

E) A) and C)
F) C) and D)

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What is the portion of the cell cycle during which the chromosomes are invisible under the light microscope because they are not yet condensed?


A) Interphase
B) Prophase
C) Metaphase
D) Anaphase

E) A) and B)
F) None of the above

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