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The leukocytes called natural killer lymphocytes


A) respond to the coating of a pathogen by complement.
B) release prostaglandins and leukotrienes in response to microbes.
C) increase in allergies and helminth infection.
D) are nonspecific leukocytes that secrete toxins onto the surface of virally infected cells.
E) are specialists in killing bacteria.

F) B) and D)
G) C) and D)

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First line of defense may be described as


A) the release of prostaglandins and leukotrienes in response to microbes.
B) damage resulting in cell lysis.
C) intact skin, mucous membranes, sebum, tears, and so forth.
D) nonspecific leukocytes that secrete toxins onto the surface of virally infected cells.
E) the coating of a pathogen by complement.

F) C) and E)
G) A) and D)

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The (epithelial/goblet/mucous) cells in the tracheal mucous membrane produce mucus.

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The normal microbiota compete with pathogens in a variety of ways to protect the body, creating a situation known as microbial (antagonism/competition/resistance).

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The absence of necessary receptors is the basis of the defense against microbial invasion known as (natural/innate/species) resistance.

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Which of the following leukocytes have granules in their cytoplasm that stain blue with methylene blue?


A) basophils
B) eosinophils
C) monocytes
D) neutrophils
E) lymphocytes

F) B) and C)
G) A) and E)

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The components of the second line of defense against microbes may be characterized as


A) responders to invasion.
B) detecting the unique features of specific pathogens.
C) passive barriers.
D) mechanisms to strengthen the first line of defense.
E) both passive barriers and detecting specific pathogen features.

F) A) and B)
G) A) and C)

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Which of the following statements about eosinophil function is true?


A) They secrete toxins onto virally infected cells.
B) They produce defensins.
C) They identify and spare normal cells.
D) They are involved in the removal of neoplastic cells.
E) They attach to the surface of parasitic helminths and produce toxins that kill the parasite.

F) C) and D)
G) A) and E)

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What is phagocytosis? What does it involve?

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Phagocytosis is a process by which a cel...

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In the case of phagocytes, positive chemotaxis involves the use of (cilia/flagella/pseudopodia) to move toward the microorganism.

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Which of the following statements regarding the surface of the skin is false?


A) It has goblet cells.
B) It is salty.
C) It is acidic.
D) It has normal microbiota.
E) It has sebum as a coating.

F) All of the above
G) A) and D)

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The oily substance that lowers the pH of the skin's surface to about pH 5 and is inhibitory to many bacteria is (sebum/sweat/serum).

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Alpha and beta interferons


A) produce active antiviral proteins (AVPs) that coat the surface of healthy cells and prevent the attachment of pathogenic viruses.
B) help protect virus- infected cells from the effects of the pathogen.
C) protect the cells that secrete them from being invaded by a virus.
D) are produced by infected fibroblasts and macrophages.
E) produce no adverse effects in the body.

F) A) and E)
G) C) and D)

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Which of the following are chemotactic factors for phagocytes?


A) interferons and chemokines
B) chemokines and peptide fragments from complement
C) peptide fragments from complement
D) interferons
E) chemokines

F) C) and D)
G) A) and E)

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The phenomenon known as chemotaxis is defined as


A) the release of prostaglandins and leukotrienes in response to microbes.
B) the coating of a pathogen by complement.
C) an increase in allergies and helminth infection.
D) the squeezing of cells through the lining of capillaries.
E) the movement of a cell toward or away from a chemical stimulus.

F) A) and E)
G) A) and D)

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The alternative pathway for complement activation is more effective than the classical pathway.

A) True
B) False

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Fever is beneficial during viral infection because the higher temperature


A) increases the effectiveness of interferons.
B) results in virus being shed in sweat.
C) prevents viral infection of fibroblasts.
D) denatures viral proteins.
E) increases vasodilation, bringing more leukocytes to the site of infection.

F) D) and E)
G) C) and D)

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Which of the following cells increase in number during a helminth infection?


A) macrophages
B) neutrophils
C) basophils
D) eosinophils
E) lymphocytes

F) A) and E)
G) C) and D)

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Which of the following characteristics is shared by the skin and mucous membranes?


A) They both have cilia.
B) Sebum may be present.
C) They are both constantly shedding and replacing cells.
D) Lysozymes are always present.
E) The outer layers are composed of dead cells.

F) B) and E)
G) B) and C)

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The process known as (complement/inflammation/phagocytosis) brings a variety of physical, chemical and cellular factors together to fight invading microorganisms.

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