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The components of the second line of defense against microbes may be characterized as


A) passive barriers.
B) responders to invasion.
C) detecting the unique features of specific pathogens.
D) mechanisms to strengthen the first line of defense.
E) both passive barriers and detecting specific pathogen features.

F) A) and B)
G) B) and D)

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What is phagocytosis? What does it involve?

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Phagocytosis is a process by which a cel...

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First line of defense may be described as


A) intact skin, mucous membranes, sebum, tears, and so forth.
B) the release of prostaglandins and leukotrienes in response to microbes.
C) damage resulting in cell lysis.
D) nonspecific leukocytes that secrete toxins onto the surface of virally infected cells.
E) the coating of a pathogen by complement.

F) B) and E)
G) A) and B)

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Which of the following are chemotactic factors for phagocytes?


A) chemokines
B) peptide fragments from complement
C) interferons
D) interferons and chemokines
E) chemokines and peptide fragments from complement

F) A) and C)
G) B) and E)

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Mucus and sweat contain which damage and kill bacteria.


A) salts
B) complement fragments
C) antimicrobial peptides
D) NOD proteins
E) antibodies

F) C) and D)
G) B) and C)

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Structures and products of pathogens that immune cells detect and respond to are called


A) NODs.
B) TLRs.
C) PAMPs.
D) leukotrienes.
E) prostaglandins.

F) A) and D)
G) C) and D)

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Response to specific pathogens that can improve with subsequent exposure is


A) the first line of defense.
B) the second line of defense.
C) the third line of defense.
D) microbial antagonism.
E) innate immunity.

F) B) and D)
G) None of the above

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Some toll-like receptors (TLRs) are found on the surface of host cells and recognize specific microbial molecules.

A) True
B) False

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Which of the following cells can use nonphagocytic means to kill bacteria?


A) neutrophils
B) eosinophils
C) natural killer cells
D) macrophages
E) both eosinophils and neutrophils

F) A) and D)
G) None of the above

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A monocyte leaves a capillary in the lungs and enters the lung tissue. It then matures to become a(n)


A) microglial cell.
B) dendritic cell.
C) goblet cell.
D) alveolar macrophage.
E) mast cell.

F) B) and D)
G) A) and B)

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Intact skin layers are part of the bodyʹs (first/second/third) line of defense against pathogens.

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Phagocytic cells in the epidermis known as contribute to its ability to prevent microbial invasion.


A) wandering macrophages
B) natural killer lymphocytes
C) dendritic cells
D) neutrophils
E) microglia

F) All of the above
G) A) and D)

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Sweat glands produce (lysozyme/dermcidin/acid), which destroys the cell wall of bacteria by cleaving the bonds between the sugar subunits present in the wall.

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The play a role in preventing neoplastic cells from progressing to cancer.


A) NK cells
B) basophils
C) mast cells
D) neutrophils
E) eosinophils

F) B) and C)
G) A) and E)

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The (epithelial/goblet/mucous) cells in the tracheal mucous membrane produce mucus.

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