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Once cytotoxic T cells are produced, which of the following is/are consistent with their ability to attack intracellular viruses?


A) Most nucleated cells process antigens through the MHC class I mechanisms.
B) Viral antigens are processed by the MHC class I mechanism and are presented to the cell surface.
C) Cytotoxic T cells bind to MHC class I processed antigens.
D) Cytotoxic T cells bound to the MHC class I processed antigens release lymphokines.
E) All of the choices are correct.

F) B) and E)
G) A) and B)

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The lymphatic system is involved in circulation, immunity, and nutrient absorption.

A) True
B) False

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Antibodies


A) play a large role in cell-mediated immunity.
B) are produced by both T and B cells.
C) are composed of four light and four heavy polypeptide chains.
D) are not specific, but act generally.
E) have a variable region that binds to a specific antigenic determinant.

F) A) and B)
G) A) and E)

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Match the term with the appropriate description. -Germinal centers


A) Lipids that cause smooth muscle relaxation and vasodilation
B) Lymph nodules aggregated in the small intestinal wall
C) Rounded epithelial structures found in the medulla of thymus
D) Areas of a lymph node where lymphocytes divide
E) A chemical released from mast cells that causes vasodilation

F) A) and E)
G) A) and D)

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The thoracic duct drains lymph into the ________.


A) left subclavian vein
B) right subclavian vein
C) right internal jugular vein
D) left brachiocephalic vein
E) left subclavian artery

F) A) and D)
G) B) and C)

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An MHC class II/antigen complex on the surface of an antigen-presenting cell (APC) binds to a T-cell receptor. What results from this interaction?


A) Other immune cells are inhibited.
B) The antigen is phagocytized by the T cell.
C) The T cell responds by directly destroying the APC.
D) Other immune cells are stimulated to respond to the antigen.

E) A) and C)
F) None of the above

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Primary lymphatic organs include the ________.


A) tonsils and spleen
B) thymus and lymph nodes
C) red bone marrow and thymus
D) red bone marrow and lymph nodes

E) All of the above
F) A) and C)

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One characteristic of the immune response is specificity. This means that


A) immunity starts in defined organs in the body.
B) immunity starts in specialized tissues in the body.
C) immunity is carried on by a specific group of cells of the immune system.
D) immunity is directed against a particular pathogen.
E) immunity is carried on by a specific group of tissues of the immune system.

F) D) and E)
G) A) and E)

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Which of the following would be classified as an innate physical barrier?


A) Activation of complement
B) Phagocytosis of invading organisms
C) Washing action of tears and saliva
D) Inflammation
E) Release of histamine

F) B) and D)
G) A) and E)

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The inflammatory response


A) prevents the spread of an infection.
B) stimulates erythrocytes to leave the blood.
C) delays healing of damaged tissues.
D) depresses immunity.
E) is harmful and should be immediately reversed.

F) A) and E)
G) C) and D)

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Which of the following most accurately describes how foreign substances can activate complement?


A) Antibodies can bind to foreign antigens and activate complement through the classical pathway.
B) Foreign substances can bind to spontaneously activated C3 and stabilize it.
C) Foreign proteins bind to C1 and activate it.
D) Foreign proteins are phagocytized by macrophages and directly activate complement.
E) Both "Antibodies can bind to foreign antigens and activate complement through the classical pathway" and "Foreign substances can bind to spontaneously activated C3 and stabilize it" are correct.

F) B) and D)
G) None of the above

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Lymph containing a high lipid content is called ________.


A) chyle
B) chyme
C) lacteal
D) interstitial fluid

E) A) and D)
F) A) and C)

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Which structural feature of lymphatic vessels is responsible to forward movement of lymph?


A) Overlapping endothelial cells
B) Valves
C) No basement membrane
D) Thin walls

E) A) and B)
F) A) and C)

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MHC class II molecules are found on ________.


A) neutrophils, monocytes, and macrophages
B) dendritic cells, B cells, and helper T cells
C) monocytes, helper T cells, and neutrophils
D) B cells, macrophages, and dendritic cells
E) B cells, C cells, and D cells

F) B) and C)
G) A) and B)

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Match the cell of adaptive immunity with its function. -Memory T cell


A) Quick and responsive to antigen, remembers previous exposure
B) After activation, differentiates to become plasma cell or memory B cell
C) Produces antibodies
D) Destroys cells by lysis or by production of cytokines
E) Activates B and effector T cells

F) B) and C)
G) A) and E)

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Lysozyme is


A) an enzyme found in body fluids that destroys certain bacteria.
B) a type of antibody that attracts a phagocyte.
C) a cytokine produced by T cells.
D) an antigen.
E) a bacteria.

F) A) and C)
G) A) and B)

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Macrophages


A) are derived from basophils.
B) reduce the inflammatory response.
C) are responsible for most phagocytic activity in the late stages of an infection.
D) produce cytokines that aid in the destruction of antigens.
E) are the first at the site of infection.

F) A) and B)
G) D) and E)

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Match the cell of adaptive immunity with its function. -Plasma cell


A) Quick and responsive to antigen, remembers previous exposure
B) After activation, differentiates to become plasma cell or memory B cell
C) Produces antibodies
D) Destroys cells by lysis or by production of cytokines
E) Activates B and effector T cells

F) B) and C)
G) D) and E)

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How do lymphatic capillaries differ from blood capillaries?


A) Lymphatic capillaries do not have a basement membrane.
B) Simple squamous epithelial cells of lymphatics overlap with loose attachments.
C) Lymphatic capillaries are more permeable than blood capillaries.
D) Lymphatic capillary epithelium act as one-way valves preventing movement of fluid back into interstitial spaces.
E) All of the choices are correct.

F) A) and D)
G) A) and C)

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The type of adaptive immunity that provides immediate protection against disease when there is no time for the person to develop their own immunity is called ________ immunity.


A) active natural
B) active artificial
C) passive innate
D) passive artificial
E) active immediate

F) B) and D)
G) C) and E)

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