Question 1

All of the following are roles of microfilaments except

Accepted Answer

A)  mitotic spindle formation.
B)  muscle cell contraction.
C)  amoeboid movement.
D)  cytoplasmic streaming.
E)  cell migration.F) C) and D)
G) D) and E)

Question 2

Elongation of the microtubule occurs by the

Accepted Answer

A)  addition of tubulin subunits to each end.
B)  addition of tubulin subunits to the (+) end.
C)  addition of the tubulin subunits to the (+) end but removal from the (-) end.
D)  addition of G-actin subunits to the (+) end.
E)  deletion of G-actin subunits from the (+) end.F) D) and E)
G) B) and E)

Question 3

Actin bundles give shape and support to the ________ found in cells of the small intestine.

Accepted Answer

A)  centrosomes
B)  microtubules
C)  microvilli
D)  nuclei
E)  lamellipodiaF) B) and E)
G) A) and B)

Question 4

The proteins of intermediate filaments (IFs)are tissue specific.Unlike microtubules or microfilaments,the amino acid composition of intermediate filaments varies from tissue to tissue.IFs are classified by the cell type or tissue in which they are found.
a. According to your text,how many classes of IF exist?
b. List the classes of IF,the IF proteins,and the tissue (or cells)in the table below.
  
c. Cells retain the IF proteins from the tissue of origin even after moving to other tissues.How is this important in the diagnosis and treatment of cancer?b.See both Table 15-4 and table below.

Accepted Answer

a. six
b. See both Table 15-4 ...

Question 5

Activation of the ________ G-protein results in the formation of focal adhesions and stress fibers.

Accepted Answer

The answer of Activation of the ________ G-protein results in...

Question 6

In binary fission,one would expect the involvement of which of the following cytoskeletal proteins?

Accepted Answer

A)  FtsZ
B)  MreB
C)  plaktin
D)  crescentin
E)  tubulinF) C) and E)
G) B) and D)

Question 7

According to the current model,which of the following is the correct sequence of microtubule assembly?

Accepted Answer

A)  dimers, oligomers, sheets of protofilaments, protofilaments, closing of microtubule, elongating microtubule
B)  dimers, sheets of protofilaments, closing of microtubule, oligomers, protofilaments, elongating microtubule
C)  dimers, oligomers, protofilaments, sheets of protofilaments, closing of microtubule, elongating microtubule
D)  protofilaments, sheets of protofilaments, closing of microtubule, elongating microtubule, dimers, oligomers
E)  dimers, oligomers, protofilaments, elongating microtubule, sheets of protofilaments, closing of microtubuleF) B) and E)
G) All of the above

Question 8

Microfilaments function in

Accepted Answer

A)  muscle contraction.
B)  cytoplasmic streaming.
C)  cell division.
D)  maintenance of cellular shape in animal cells.
E)  all of the aboveF) A) and B)
G) A) and C)

Question 9

Activation of the ________ G-protein results in the extension of lamellipodia.

Accepted Answer

The answer of Activation of the ________ G-protein results in...

Question 10

Based upon your knowledge of the cytoskeleton,explain how the discovery of cytoskeletal elements in prokaryotes contributed to the current understanding of the endosymbiont theory.

Accepted Answer

The discovery of progenitor proteins wit...

Question 11

The ________ model is used to describe the simultaneous polymerization and depolymerization of microtubules.

Accepted Answer

The answer of The ________ model is used to describe...

Question 12

________ are associated with the "pinching in" of the cell membrane during cytokinesis.

Accepted Answer

The answer of ________ are associated with the "pinching in"...

Question 13

Many drugs have the ability to disrupt the cytoskeletal structure of the cell.These drugs are useful in the study of microtubules and microfilaments.
a. What are some of the drugs used to study microfilaments?
b. What are some of the drugs used to study microtubules?
c. What additional technique with applications similar to these drugs is often used to study the cytoskeleton?
d. Cancer is a disease in which cells divide uncontrollably.Many of the drugs used in the study of microtubules are also used in the treatment of cancer.From what you know about microtubules and microfilaments,can you suggest why drugs that disrupt microtubules are more useful in the treatment of cancer than drugs used to disrupt microfilaments?
e. These anticancer drugs are in a category of drugs that describes their function.What is the category?

Accepted Answer

a. cytochalasin D,latrunculin A,phalloid...

Question 14

The minus (-) ends of microtubules are often anchored at the ________________ ,such that the dynamics associated with microtubules is at the plus (+) ends.

Accepted Answer

A)  centriole
B)  centrosome
C)  plasma membrane
D)  centromere
E)  mitochondrial outer membraneF) None of the above
G) A) and D)

Question 15

Choose the item that best matches the other items.
-capping protein

Accepted Answer

A)  breaking and capping actin
B)  increase cellular surface area
C)  assembly and disassembly
D)  terminal web
E)  control microtubule organizationF) plectinG) central shaftH) nucleating actin branchesI) bind to profilin and CapZJ) oligomer formationK) nucleating tubulin branchesL) hemidesmosomeM) decorate the actin microfilamentN) dyneinO) prevents loss of subunitsP) desmosome  Q) nuclear lamina  R) account for 10-15% of microtubules  S) inhibits microtubule assembly  T) two identical polypeptides joined end-to-end  U) found in cilia and flagellaV) O) and Q)
W) G) and M)

Question 16

The ________ is a complex network of interconnected filaments and tubules that extends throughout the cytosol,from the nucleus to the inner surface of the plasma membrane.

Accepted Answer

A)  cytoskeleton
B)  microtubule apparatus
C)  cell scaffold
D)  desmin sheath
E)  microfilament arrayF) B) and C)
G) A) and E)

Question 17

Choose the item that best matches the other items.
-nonmotor MAPs

Accepted Answer

A)  breaking and capping actin
B)  increase cellular surface area
C)  assembly and disassembly
D)  terminal web
E)  control microtubule organizationF) plectinG) central shaftH) nucleating actin branchesI) bind to profilin and CapZJ) oligomer formationK) nucleating tubulin branchesL) hemidesmosomeM) decorate the actin microfilamentN) dyneinO) prevents loss of subunitsP) desmosome  Q) nuclear lamina  R) account for 10-15% of microtubules  S) inhibits microtubule assembly  T) two identical polypeptides joined end-to-end  U) found in cilia and flagellaV) F) and P)
W) K) and S)

Question 18

Capping proteins such as CapZ

Accepted Answer

A)  cause microtubules to lengthen.
B)  destabilize microtubules.
C)  stabilize microtubules.
D)  cause microtubules branching.
E)  connect microtubules to microfilaments.F) B) and D)
G) A) and D)

Question 19

Match between columns
                        Premises: axonemal microtubules

Accepted Answer

The Answer of nucleating actin branches and account for 10-15% is...

Question 20

Which of the following proteins is associated with the precise control of where microtubules form and depolymerize?

Accepted Answer

A)  Tau
B)  stathmin/Op18
C)  kinesin
D)  catastrophins
E)  MAP 2F) D) and E)
G) C) and D)

Exam 15: Cytoskeletal Systems

Elongation of the microtubule occurs by the

Correct Answer
verified

Correct Answer
verified
a. six
b. See both Table 15-4 ...
View Answer

Activation of the ________ G-protein results in the extension of lamellipodia.

Correct Answer
verified

The ________ model is used to describe the simultaneous polymerization and depolymerization of microtubules.

Correct Answer
verified

The ________ is a complex network of interconnected filaments and tubules that extends throughout the cytosol,from the nucleus to the inner surface of the plasma membrane.

Correct Answer
verified

Based upon your knowledge of the cytoskeleton,explain how the discovery of cytoskeletal elements in prokaryotes contributed to the current understanding of the endosymbiont theory.

Correct Answer
verified
The discovery of progenitor proteins wit...
View Answer

Capping proteins such as CapZ

Correct Answer
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Choose the item that best matches the other items. -nonmotor MAPs

Correct Answer
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Activation of the ________ G-protein results in the formation of focal adhesions and stress fibers.

Correct Answer
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The minus (-) ends of microtubules are often anchored at the ________________ ,such that the dynamics associated with microtubules is at the plus (+) ends.

Correct Answer
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In binary fission,one would expect the involvement of which of the following cytoskeletal proteins?

Correct Answer
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All of the following are roles of microfilaments except

Correct Answer
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________ are associated with the "pinching in" of the cell membrane during cytokinesis.

Correct Answer
verified

According to the current model,which of the following is the correct sequence of microtubule assembly?

Correct Answer
verified

Which of the following proteins is associated with the precise control of where microtubules form and depolymerize?

Correct Answer
verified

Microfilaments function in

Correct Answer
verified

Actin bundles give shape and support to the ________ found in cells of the small intestine.

Correct Answer
verified

Choose the item that best matches the other items. -capping protein

Correct Answer
verified

Correct Answer
verified
a. cytochalasin D,latrunculin A,phalloid...
View Answer

Choose the item that best matches the other items.

Exam 15: Cytoskeletal Systems

Elongation of the microtubule occurs by the

Correct AnswerverifiedShow Answer

Correct Answerverifieda. sixb. See both Table 15-4 ...View AnswerShow Answer

Activation of the ________ G-protein results in the extension of lamellipodia.

Correct AnswerverifiedShow Answer

The ________ model is used to describe the simultaneous polymerization and depolymerization of microtubules.

Correct AnswerverifiedShow Answer

The ________ is a complex network of interconnected filaments and tubules that extends throughout the cytosol,from the nucleus to the inner surface of the plasma membrane.

Correct AnswerverifiedShow Answer

Based upon your knowledge of the cytoskeleton,explain how the discovery of cytoskeletal elements in prokaryotes contributed to the current understanding of the endosymbiont theory.

Correct AnswerverifiedThe discovery of progenitor proteins wit...View AnswerShow Answer

Capping proteins such as CapZ

Correct AnswerverifiedShow Answer

Choose the item that best matches the other items. -nonmotor MAPs

Correct AnswerverifiedShow Answer

Activation of the ________ G-protein results in the formation of focal adhesions and stress fibers.

Correct AnswerverifiedShow Answer

The minus (-) ends of microtubules are often anchored at the ________________ ,such that the dynamics associated with microtubules is at the plus (+) ends.

Correct AnswerverifiedShow Answer

In binary fission,one would expect the involvement of which of the following cytoskeletal proteins?

Correct AnswerverifiedShow Answer

All of the following are roles of microfilaments except

Correct AnswerverifiedShow Answer

________ are associated with the "pinching in" of the cell membrane during cytokinesis.

Correct AnswerverifiedShow Answer

According to the current model,which of the following is the correct sequence of microtubule assembly?

Correct AnswerverifiedShow Answer

Which of the following proteins is associated with the precise control of where microtubules form and depolymerize?

Correct AnswerverifiedShow Answer

Microfilaments function in

Correct AnswerverifiedShow Answer

Actin bundles give shape and support to the ________ found in cells of the small intestine.

Correct AnswerverifiedShow Answer

Choose the item that best matches the other items. -capping protein

Correct AnswerverifiedShow Answer

Correct Answerverifieda. cytochalasin D,latrunculin A,phalloid...View AnswerShow Answer

Choose the item that best matches the other items.

Correct Answer
verified

Correct Answer
verified
a. six
b. See both Table 15-4 ...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
The discovery of progenitor proteins wit...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
a. cytochalasin D,latrunculin A,phalloid...
View Answer