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The rabies virus travels to the CNS via


A) anterograde axoplasmic transport.
B) retrograde axoplasmic transport.
C) blood vessels.
D) subcutaneous connective tissue.
E) cerebrospinal fluid.

F) A) and B)
G) B) and E)

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The effect that a neurotransmitter has on the postsynaptic membrane depends on the


A) frequency of neurotransmitter release.
B) nature of the neurotransmitter.
C) characteristics of the receptors.
D) quantity of neurotransmitters released.
E) All of the answers are correct.

F) A) and E)
G) A) and D)

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Ions can move across the plasma membrane in which of the following ways?


A) through voltage-gated channels as in the action potential
B) through passive or leak channels
C) by ATP-dependent ion pumps like the sodium-potassium exchange pump
D) through chemically gated channels as in neuromuscular transmission
E) All of the answers are correct.

F) All of the above
G) None of the above

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The plasma membrane of an axon is called the


A) axon terminal.
B) neurilemma.
C) myelin sheath.
D) sarcolemma.
E) axolemma.

F) B) and C)
G) A) and E)

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The buildup of depolarization when EPSPs arrive in rapid succession is called ________ summation.


A) temporal
B) spatial
C) electrical
D) chemical
E) perforal

F) D) and E)
G) A) and B)

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How would a chemical that prevents the opening of voltage-regulated Na+ channels affect the function of a neuron?


A) The neuron will only be able to hyperpolarize.
B) The neuron will depolarize more rapidly.
C) Action potentials will lack a repolarization phase.
D) The neuron will automatically and repeatedly produce graded potentials.
E) The neuron will only be capable of producing graded potentials.

F) C) and D)
G) B) and E)

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When pressure is applied to neural tissue,all of the following effects are possible except


A) a decrease in blood flow.
B) a decrease in available oxygen.
C) a change in neuron excitability
D) glial cells degenerate.
E) neurons are triggered to divide.

F) A) and B)
G) A) and C)

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Opioids relieve pain by blocking the release of


A) substance O.
B) substance P.
C) substance Q.
D) substance X.
E) None of the answers is correct.

F) B) and C)
G) B) and D)

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Which of the following is not true regarding the establishment of a neuron's resting potential?


A) Chemical and electrical forces both favor sodium ions entering the cell.
B) Electrical forces push sodium ions into the cell.
C) The chemical gradient for potassium ions tends to drive them out of the cell.
D) Ion pumps in the plasma membrane eject sodium ions as fast as they cross the membrane.
E) Resting membrane permeability to Na⁺ is very low.

F) A) and E)
G) D) and E)

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In which of the following would the rate of impulse conduction be the greatest?


A) a myelinated fiber of 10-µm diameter
B) a nonmyelinated fiber of 20-µm diameter
C) a myelinated fiber of 1-µm diameter
D) a nonmyelinated fiber of 10-µm diameter
E) It would be the same in all because of the all-or-none principle.

F) C) and E)
G) A) and C)

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Rapid impulse conduction from "node" to "node" is called


A) spatial propagation.
B) saltatory propagation.
C) divergent propagation.
D) synaptic transmission.
E) continuous propagation.

F) C) and E)
G) All of the above

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Type ________ fibers have the largest diameter axons.


A) S
B) F
C) A
D) B
E) C

F) B) and D)
G) B) and C)

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The ________ division of the nervous system carries motor commands to muscles and glands.


A) spinal
B) peripheral
C) autonomic
D) afferent
E) efferent

F) B) and C)
G) None of the above

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How does blocking retrograde axoplasmic transport in an axon affect the activity of a neuron?


A) The neuron becomes unable to produce neurotransmitters.
B) The neuron becomes unable to produce action potentials.
C) The soma becomes unable to export products to the synaptic terminals.
D) The soma becomes unable to respond to changes in the distal end of the axon.
E) The neuron becomes unable to depolarize when stimulated.

F) B) and D)
G) A) and E)

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Neurons that are rare,small,and lack features that distinguish dendrites from axons are called


A) anaxonic.
B) unipolar.
C) bipolar.
D) tripolar.
E) multipolar.

F) A) and E)
G) B) and D)

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Which of the following is not a function of the neuroglia?


A) support
B) memory
C) secretion of cerebrospinal fluid
D) maintenance of blood-brain barrier
E) phagocytosis

F) A) and E)
G) A) and D)

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   Figure 12-1 The Neuron Use Figure 12-1 to answer the following questions: -The structure labeled  2  is a(n)  A) neurofilament. B) dendrite. C) initial segment. D) perikaryon. E) axon. Figure 12-1 The Neuron Use Figure 12-1 to answer the following questions: -The structure labeled "2" is a(n)


A) neurofilament.
B) dendrite.
C) initial segment.
D) perikaryon.
E) axon.

F) B) and E)
G) D) and E)

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The sodium-potassium ion exchange pump


A) must reestablish ion concentrations after each action potential.
B) transports sodium ions into the cell during depolarization.
C) transports potassium ions out of the cell during repolarization.
D) moves sodium and potassium opposite to the direction of their electrochemical gradients.
E) depends on a hydrogen gradient for energy.

F) A) and E)
G) B) and C)

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   Figure 12-2 The Nerve Action Potential Use Figure 12-2 to answer the following questions: -Which area of the graph shows when voltage-gated sodium channels are open? A) 2 B) 4 C) 1 D) 5 E) 3 Figure 12-2 The Nerve Action Potential Use Figure 12-2 to answer the following questions: -Which area of the graph shows when voltage-gated sodium channels are open?


A) 2
B) 4
C) 1
D) 5
E) 3

F) B) and C)
G) B) and E)

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The sensory loss and muscle weakness associated with multiple sclerosis are a consequence of


A) excessive myelin layers around the axonal fibers.
B) demyelination.
C) a neuron not having a myelin sheath.
D) a neuron without a neurilemma.
E) too few nodes of Ranvier.

F) A) and E)
G) A) and C)

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