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The serum of a person with blood type A and Rh- will have the ability to make which of the following antibodies?


A) Anti-B
B) Anti-A
C) Anti-A, anti-B, and anti-Rh
D) Anti-A and anti-Rh
E) Anti-B and anti-Rh

F) All of the above
G) D) and E)

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Tissue transplanted from one body site on a patient to a different body site on that patient is called a(n) ______.


A) allograft
B) xenograft
C) isograft
D) hypograft
E) autograft

F) C) and E)
G) A) and D)

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Place these events in the pathogenesis of contact dermatitis in order,with 1 being the first step. Sensitized T lymphocytes recognize the antigen and make cytokine chemicals. Cytokine chemicals attract macrophages,dendritic cells,and cytotoxic T lymphocytes to the site of the antigen. Chemicals are released from phagocytic cells and cytotoxic T cells,resulting in host tissue damage. A chemical is absorbed through the skin. The antigen is identified by a dendritic cell.

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What may result when grafted tissue such as bone marrow contains passenger lymphocytes?


A) Formation of autoantibodies
B) Host rejection of graft
C) Hypogammaglobulinemia
D) Graft versus host disease

E) A) and B)
F) A) and C)

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Infection with enteroviruses,such as rotavirus and cytomegalovirus,has been implicated in the onset of type I diabetes.This area of research involves the study of ______.


A) molecular mimicry
B) forbidden clones
C) the gut microbiome
D) sequestered antigens

E) All of the above
F) A) and B)

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The most common immunoglobulin deficiency is an IgG deficiency.

A) True
B) False

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All of the following represent potential therapy for patients with SCID except


A) stem cell grafts.
B) graft versus host.
C) transfusion with adensosine deaminase.
D) gene therapy.
E) bone marrow transplants.

F) None of the above
G) A) and B)

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In multiple sclerosis,autoantibodies attack


A) sodium pump proteins in the cell membrane.
B) acetylcholine receptors on skeletal muscle.
C) acetylcholine receptors on smooth muscle.
D) cells in thyroid follicles.
E) myelin sheath cells of the nervous system.

F) B) and E)
G) All of the above

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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During graft rejection,cytotoxic T cells of the recipient recognize and respond to foreign class I MHC receptors on the grafted cells.

A) True
B) False

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An antihistamine will


A) bind to histamine receptors on target organs.
B) reverse spasms of respiratory smooth muscles.
C) block synthesis of leukotrienes.
D) inhibit the activity of lymphocytes.

E) B) and C)
F) All of the above

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Transfusion of the wrong blood type can cause


A) recipient antibody activation of the complement cascade to attack the RBCs.
B) fever and anemia.
C) systemic shock and kidney failure.
D) massive hemolysis of the donor RBCs.
E) All of the choices are correct.

F) B) and D)
G) D) and E)

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Fungal spores and animal dander are considered to be which type of allergen?


A) Injectant
B) Contactant
C) Inhalant
D) Ingestant

E) A) and B)
F) All of the above

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Corticosteroids will


A) inhibit the activity of lymphocytes.
B) bind to histamine receptors on target organs.
C) block synthesis of leukotrienes.
D) reverse spasms of respiratory smooth muscles.

E) None of the above
F) B) and C)

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DiGeorge syndrome is the result of


A) autoantibodies.
B) a genetic defect in the development of both T cells and B cells.
C) delayed hypersensitivity.
D) congenital absence or immaturity of the thymus gland.
E) failure of B-cell development and maturity.

F) A) and B)
G) All of the above

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AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

A) True
B) False

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Systemic anaphylaxis can quickly result in airway blockage,shock,and death.

A) True
B) False

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The initial encounter with an allergen is called the _____ dose.


A) sensitizing
B) provocative
C) allergic
D) hypersensitivity
E) desensitizing

F) B) and C)
G) None of the above

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All of the following are autoimmune diseases except


A) type I diabetes.
B) metastatic cancer.
C) systemic lupus erythematosus.
D) rheumatoid arthritis.
E) Graves'disease.

F) All of the above
G) A) and E)

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Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen-antibody complexes occurs in


A) hemolytic disease of the newborn.
B) anaphylaxis.
C) serum sickness.
D) delayed hypersensitivity.

E) A) and C)
F) A) and B)

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