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Pineal gland production of melatonin is stimulated by the _______________ of the hypothalamus.


A) supraoptic nuclei
B) paraventricular nuclei
C) suprachiasmatic nucleus
D) None of the choices are correct.

E) A) and B)
F) B) and C)

Correct Answer

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Molecules that are produced within one tissue but regulate a different tissue of the same organ are called


A) autocrine regulators.
B) endocrine regulators.
C) paracrine regulators.
D) exocrine regulators.

E) A) and B)
F) A) and C)

Correct Answer

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Most polypeptide and protein hormones are synthesized as prohormones.

A) True
B) False

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A chronically high hormone concentration often leads to an increased receptor number.

A) True
B) False

Correct Answer

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Stomach irritation by NSAIDs like aspirin is believed to be the result of


A) inhibition of PGI2 and PGE2.
B) secretion of PGI2 and PGE2.
C) inhibition of thromboxane A2.
D) None of the choices are correct.

E) B) and D)
F) B) and C)

Correct Answer

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How is most thyroid hormone transported in the plasma?


A) as T4 bonded to globulin
B) as T3 bonded to globulin
C) as free T4
D) as free T3

E) A) and B)
F) B) and D)

Correct Answer

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Polypeptide and glycoprotein hormones can be taken orally.

A) True
B) False

Correct Answer

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Increased circulating concentrations of testosterone would stimulat


A) decreased secretion of growth hormone.
B) decreased secretion of adrenocorticotropin.
C) decreased secretion of luteinizing hormone.
D) decreased secretion of thyroid stimulating hormone.

E) A) and B)
F) B) and D)

Correct Answer

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_____________ inhibits COX3 in the brain which results in pain and fever reduction.


A) Acetaminophen (Tylenol)
B) Aspirin
C) Ibuprofen (Motrin)
D) All of the choices are correct.

E) B) and C)
F) A) and B)

Correct Answer

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What is needed to control secretion of melatonin from the pineal gland?


A) sympathetic stimulation from the suprachiasmatic nucleus of the hypothalamus
B) activation of melanopsin from ganglion cells of the retina
C) sunlight or lack of sunlight
D) All of the choices are correct.

E) A) and D)
F) All of the above

Correct Answer

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What is the cause of pituitary cachexia?


A) over-secretion of growth hormone in adults
B) over-secretion of prolactin in adults
C) deficiency of growth hormone in adults
D) deficiency of growth hormone in children

E) None of the above
F) B) and C)

Correct Answer

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A deficiency of dietary cholesterol would decrease the production of


A) glucagon.
B) atrial natriuretic hormone.
C) melatonin
D) estradiol-17b.

E) All of the above
F) B) and D)

Correct Answer

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Hormones which enhance the responsiveness of a target organ to a second hormone have


A) complementary effects.
B) synergistic effects.
C) antagonistic effects.
D) permissive effects.

E) B) and C)
F) A) and D)

Correct Answer

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Which of the following is NOT a symptom of Addison's disease?


A) skin discoloration (bronzing)
B) hyperglycemia
C) hypotension
D) sodium and potassium imbalances

E) A) and C)
F) All of the above

Correct Answer

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A deficiency of dietary iodine would result in excessive TSH secretion.

A) True
B) False

Correct Answer

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Nuclear receptors that have been identified and their genes cloned,but their hormone ligands are unknown are called


A) transcription factors.
B) unknown ligands.
C) orphan receptors.
D) nongenomic receptors.

E) All of the above
F) A) and D)

Correct Answer

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Many polypeptide and glycoprotein hormones are secreted in discrete bursts called pulsatile secretions.

A) True
B) False

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