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Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measure of DNA levels ranged from 3 to 6 picograms per nucleus. One nucleus had 5 picograms of DNA. What stage of the cell cycle was the nucleus in?


A) G0
B) G1
C) S
D) G2
E) M

F) B) and D)
G) A) and B)

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All of the following occur during the latter stages of mitotic prophase EXCEPT


A) the coiling of chromosomes.
B) the division of centromeres.
C) the formation of spindles.
D) the synthesis of DNA.
E) the degradation of the nuclear envelope.

F) B) and D)
G) A) and B)

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Multicellular organisms undergo mitotic cell division to


A) produce new organisms.
B) produce gametes.
C) increase the variability of the population.
D) increase the size of the organism.
E) facilitate sexual reproduction.

F) None of the above
G) B) and C)

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If cells in the process of dividing are subjected to colchicines, a drug that interferes with the functioning of the spindle fibers, at which stage will mitosis be arrested?


A) anaphase
B) prophase
C) telophase
D) metaphase
E) interphase

F) D) and E)
G) A) and C)

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Cells grown in a petri dish tend to divide until they form a thin layer covering the bottom of the dish. If cells are removed from the middle of the dish, the cells bordering the open space will begin dividing until they have filled the empty space. What does this experiment show?


A) When cells come into contact with other cells, they stop growing.
B) The controls on cell growth and division can be turned on and off.
C) Cell division can be regulated by factors outside of the cell.
D) Cells continue to grow as long as there is adequate space.
E) All answers are valid and correct.

F) B) and C)
G) B) and E)

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A mutation results in a cell that no longer produces a normal protein kinase for the M-phase checkpoint. Which of the following would likely be the immediate result of this mutation?


A) The cell would prematurely enter anaphase.
B) The cell would never leave metaphase.
C) The cell would never enter metaphase.
D) The cell would never enter prophase.
E) The cell would undergo normal mitosis, but fail to enter the next G1.

F) C) and E)
G) B) and E)

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Cytokinesis usually, but not always, follows mitosis. If a cell undergoes mitosis and not cytokinesis, this would result in


A) a cell with a single large nucleus.
B) a cell with two or more nuclei.
C) cells with abnormally small nuclei.
D) feedback responses that prevent mitosis.
E) death of the cell line.

F) A) and B)
G) C) and D)

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Rebecca found out that she has a mass of dividing cells called a tumor in her ovaries. She has had tests and is returning to the doctor. What would the best results the doctor could tell her be?


A) It is a benign tumor.
B) The cells are cancerous and are in situ.
C) It is a malignant tumor.
D) It is malignant ovarian cancer.
E) The tumor has metastasized and invaded neighboring tissue.

F) A) and E)
G) C) and E)

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A

A cell is inhibited during the S phase of its cycle. It will not reproduce due to lack of


A) ATP availability.
B) centriole migration.
C) centromere formation.
D) DNA synthesis.
E) plasma membrane structure.

F) B) and C)
G) D) and E)

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D

Movement of chromosomes during anaphase would be most affected by a drug that


A) reduced cyclin concentrations.
B) increased cyclin concentrations.
C) prevented elongation of microtubules.
D) prevented shortening of microtubules.
E) prevented attachment of the microtubules to the kinetochore.

F) C) and D)
G) B) and E)

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Which following pair is correctly matched?


A) G1 phase - DNA replication
B) G2 phase - preparation for meiosis
C) S phase - DNA replication
D) M phase - cell growth
E) G0 phases - cell growth

F) C) and D)
G) A) and C)

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If a cell has 46 chromosomes at the beginning of mitosis, then at the end of anaphase there would be a total of


A) 23 chromatids.
B) 23 chromosomes.
C) 46 chromotids.
D) 46 chromosomes.
E) 92 chromosomes.

F) None of the above
G) A) and B)

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The mitotic spindle is composed of ______________ and grows from the _______________ toward the center of the cell.


A) microtubules; centrosome
B) asters; spindle equator
C) centrosomes; aster
D) microtubules; chromatid
E) microtubules; cleavage furrow

F) All of the above
G) A) and D)

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The looping of DNA around histone proteins


A) produces the characteristic helix shape of the DNA.
B) allow the room for cellular machinery to reach all genes so they may be transcribed.
C) compacts the DNA allowing a large amount of DNA to fit into the cell.
D) prevents the DNA from becoming kinked and breaking.
E) occurs when the DNA is damaged and allow the cell to be destroyed through apoptosis.

F) None of the above
G) All of the above

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If there are twenty centromeres in a cell, how many chromosomes are there?


A) 10
B) 20
C) 30
D) 40
E) 80

F) B) and C)
G) C) and D)

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Unicellular organisms undergo mitotic division to


A) repair damaged cells.
B) increase the size of the organism.
C) produce new organisms.
D) increase the genetic variability of the population.
E) produce gametes.

F) C) and D)
G) A) and C)

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The G2 checkpoint prevents the cell cycle from continuing until ________.


A) DNA is completely replicated
B) damage to DNA can be repaired
C) replicated DNA is separated
D) organelles have been duplicated
E) DNA is completely replicated AND damage to DNA can be repaired

F) All of the above
G) A) and B)

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E

Which of the following represents the phases of mitosis in their proper sequence?


A) prophase, metaphase, anaphase, telophase
B) interphase, prophase, metaphase, telophase
C) anaphase, interphase, prophase, metaphase, telophase
D) prophase, metaphase, anaphase, telophase, cytokinesis
E) metaphase, interphase, cytokinesis, anaphase, telophase

F) A) and B)
G) A) and E)

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Cytokinesis in plants occurs as _______________ and in animals as ________________.


A) actin fibers pull the membrane inward until the two sides touch; the Golgi apparatus produces membrane bound vesicles filled with materials to make the cell wall.
B) the Golgi apparatus produces membrane bound vesicles filled with materials to make the cell wall; actin fibers pull the membrane inward until the two sides touch.
C) the centrosome produces membrane bound vesicles filled with materials to make the cell wall; the Golgi apparatus produces actin fibers to pull the membrane inward until the two sides touch.
D) actin fibers interact to make the cell wall; the cleavage furrow pulls the membrane inward until the two sides touch.
E) the Golgi apparatus produces a cleavage furrow; actin fibers pull the membrane inward until the two sides touch.

F) C) and E)
G) B) and E)

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Nuclear division is represented in the figure below by the letter ___. Nuclear division is represented in the figure below by the letter ___.   A)  a B)  b C)  c D)  d E)  e


A) a
B) b
C) c
D) d
E) e

F) B) and C)
G) A) and B)

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