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An allele that masks the effect of another is


A) homozygous.
B) heterozygous.
C) recessive.
D) dominant.

E) C) and D)
F) A) and B)

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The genotypes and phenotypes that result from a cross of AA and Aa (A = normal pigmentation and a = albinism) are


A) phenotypes-all normal;genotypes-50% homozygous dominant and 50% heterozygous.
B) phenotypes-50% normal and 50% albino;genotypes-all heterozygous.
C) phenotypes-75% norma and 25% albino;genotypes-75% heterozygous and 25% homozygous.
D) phenotypes-all albino;genotypes-50% heterozygous and 50% homozygous recessive.

E) C) and D)
F) B) and D)

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A trait determined by more than one gene is polygenic.

A) True
B) False

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Genes have multiple alleles that differ in DNA sequence because a gene consists of many nucleotides,each of which can be any of four types.

A) True
B) False

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Polydactyly is an example of a trait that is both ___________ and variably expressive.


A) incompletely penetrant
B) pleiotropic
C) multifactorial
D) completely penetrant

E) All of the above
F) B) and C)

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Janet is homozygous dominant for the wild type allele of the gene that when mutant causes cystic fibrosis.Her brother Henry is a heterozygote.They both do not have the disease cystic fibrosis.

A) True
B) False

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An allele that is not expressed in the heterozygous condition is


A) recessive.
B) dominant.
C) autosomal.
D) codominant.

E) A) and D)
F) A) and C)

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The two general types of chromosomes are


A) autosomes and allosomes.
B) sex chromosomes and allosomes.
C) sex chromosomes and autosomes.
D) X and Y chromosomes.

E) A) and D)
F) B) and C)

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A person normally has two alleles of a gene because


A) DNA only comes in two forms.
B) one allele of a gene is carried on each of two homologous chromosomes.
C) there isn't enough DNA to accommodate more than this.
D) all genes come in only two varieties.

E) A) and D)
F) A) and C)

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The human genome consists of


A) DNA,most of which encodes protein.
B) DNA,most of which does not encode protein.
C) protein,most of which encodes DNA.
D) protein,most of which does not encode DNA.

E) None of the above
F) C) and D)

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Most of the DNA in the human genome encodes protein.

A) True
B) False

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A pharmacogenetic test can reveal whether a certain drug will be effective and/or cause adverse effects in a particular person.

A) True
B) False

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A gene typically has many alleles because


A) humans have many traits.
B) a chromosome has many genes.
C) a DNA sequence can vary in many ways.
D) a protein sequence can vary in many ways.

E) A) and D)
F) A) and C)

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Hemophilia A is


A) due to an X-linked dominant gene.
B) passed from affected males to their sons.
C) more common in females.
D) a defect in the clotting mechanism.

E) A) and D)
F) A) and C)

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The field of genetics deals only with disease.

A) True
B) False

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The nuances of eye color arise from


A) the numbers of rods and cones in the retinA.
B) the way pigments are deposited in the iris.
C) how much vitamin A is in a person's diet.
D) multiple alleles of at least 10 genes.

E) None of the above
F) C) and D)

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The genotypes and phenotypes that result from the cross of Aa and Aa (A = normal pigmentation and a = albinism) are


A) phenotypes-75% normal and 25% albino;genotypes-25% homozygous dominant and 50% heterozygous and 25% homozygous recessive.
B) phenotypes-50% normal and 50% albino;genotypes-all homozygous recessive.
C) phenotypes-50% normal and 50% albino;genotypes-50% homozygous recessive and 50% homozygous dominant.
D) phenotypes-25% normal and 75% albino;genotypes-25% homozygous dominant and 50% heterozygous and 25% homozygous recessive.

E) All of the above
F) B) and D)

Correct Answer

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Gender determination for males reflects expression of


A) the SRY gene but not the Wnt4 gene.
B) the Wnt4 gene but not the SRY gene.
C) both the SRY and Wnt4 genes.
D) the entire Y chromosome.

E) None of the above
F) B) and D)

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The human genome contains millions of different genes.

A) True
B) False

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Gametes pass genetic information from generation to generation.

A) True
B) False

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