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Which of the following does not describe actions of interferon (IFN) ?


A) IFN binds to normal, uninfected cells stimulating the activation of genes that produce anti-viral proteins.
B) IFN can penetrate the viral capsid and destroy the virus.
C) Virally infected cells can release interferon which attracts NK cells to attack and kill the IFN secreting cell.
D) IFN will attract macrophages to the secreting cell to be removed by phagocytosis.

E) A) and D)
F) B) and C)

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    Figure 21.1 Using Figure 21.1, match the following: -Variable region. A) B B) D C) A D) E E) C Figure 21.1 Using Figure 21.1, match the following: -Variable region.


A) B
B) D
C) A
D) E
E) C

F) A) and D)
G) C) and D)

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Which immunoglobulin class is attached to the external surface of B cells and acts as an antigen receptor of the B cell?


A) IgE
B) IgD
C) IgG
D) IgM
E) IgA

F) None of the above
G) B) and D)

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Match the following: -Second line of defense.


A) Intact skin and mucous membranes
B) Inflammatory response and skin and mucous membranes
C) Inflammatory response
D) Immune response

E) A) and C)
F) B) and C)

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Which of the following is not a mechanism for the development of autoimmune disorders?


A) cross-reaction of antibodies formed against foreign antigens (haptens) bound with self-antigens
B) mutation followed by the appearance of membrane proteins not previously present
C) exposure of previously "hidden" self-antigens to the adaptive immune system during trauma
D) a second exposure to an allergen

E) A) and B)
F) A) and C)

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What is the role of interferon in defense against disease?


A) protects cells that have not yet been infected by viruses
B) activates the inflammatory process
C) activates the complement mechanism
D) protects cells that have not yet been infected by bacteria

E) All of the above
F) A) and B)

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Antibody functions include all of the following except ________.


A) targeting foreign cells so that complement proteins can cause cellular lysis
B) cross-linking cell-bound antigens on red blood cells when blood types are properly matched
C) linking soluble antigens together so that they fall out of solution
D) binding and inactivating chemical toxins released by bacteria or other microorganisms

E) A) and D)
F) B) and C)

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When the white blood cell count is depressed,the classic signs of infection such as redness,heat,and swelling are not manifested.In this case,the nurse should avoid administering aspirin.Explain why.

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Aspirin would disgui...

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Inflammation ________.


A) is caused by bacterial activity to enhance the spread of disease
B) brings more leukocytes to the sight of infection
C) is caused by viral activity to enhance the spread of the disease
D) slows the healing process with swelling that can impair bodily function

E) A) and D)
F) A) and B)

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A vaccine is effective because ________.


A) B-lymphocytes are unable to mount an immune response the first time they are exposed to a new pathogen
B) the secondary response of the adaptive immunity is faster and more efficient the primary response
C) the vaccine contains the lymphocytes necessary to fight infection
D) the vaccine contains the antibodies necessary to fight infection

E) A) and B)
F) B) and C)

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Select the best description of the negative selection process of lymphocyte maturation.


A) removal of lymphocytes that fail to recognize "self" cells
B) teaching a lymphocyte to recognize "self" from foreign antigens
C) removal of lymphocytes that react with "self" cells
D) allowing the survival of lymphocytes that cannot bind to MHC proteins

E) None of the above
F) A) and D)

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Which of the following is not a complement activation pathway?


A) lectin pathway
B) alternative pathway
C) lactate pathway
D) classical pathway

E) B) and C)
F) A) and C)

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All but one of the following occur during the inflammatory response.Select the example below that does not describe the process of inflammation.


A) Vasoconstriction will prevent excessive blood loss due to injury.
B) Chemotaxis draws leucocytes to the site of injury.
C) Increases capillary permeability.
D) Release of prostaglandins resulting in pain.

E) None of the above
F) B) and C)

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A woman comes into the hospital emergency room complaining that she is having problems swallowing and her neck is swelling.She has a history of radiation treatment to her neck as a child for acne.What could be the problem?

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The woman is suffering from Hashimoto's ...

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Match the following: -Forms antibody producing cells.


A) Regulatory T cell
B) Memory cell
C) Helper T cell
D) B cell
E) Cytotoxic T cell

F) B) and E)
G) A) and D)

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Soluble proteins secreted by plasma cells are called antibodies.

A) True
B) False

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Which of the following is not a function of the inflammatory response?


A) prevents the spread of the injurious agent to nearby tissue
B) disposes of cellular debris and pathogens
C) replaces injured tissues with connective tissue
D) sets the stage for repair processes

E) A) and C)
F) A) and D)

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B lymphocytes develop immunocompetence in the ________.


A) bone marrow
B) lymph nodes
C) thymus
D) spleen

E) A) and D)
F) A) and C)

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Which of the following is characteristic of complete antigens?


A) inhibit production of antibodies
B) contain many repeating chemical units
C) small molecules
D) reactivity with an antibody

E) None of the above
F) B) and C)

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Choose the best description of an antigen.


A) part or a piece of a disease or pathogen
B) a particle that triggers the adaptive immunity
C) a particle (typically a foreign protein) that triggers inflammation
D) a chemical that enhances or modifies immune response

E) None of the above
F) All of the above

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