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What do BRCA1 and p53 have in common?


A) Both cause breast cancer.
B) Both cause eye cancers.
C) Both are oncogenes.
D) Both are tumor suppressors.
E) Both are inherited as autosomal dominant traits.

F) A) and B)
G) C) and E)

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In the case of a proto-oncogene like Ras, both copies of the gene must be mutated to increase a predisposition to cancer.

A) True
B) False

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When the p53 gene is overexpressed in normal cells, the cells are killed.

A) True
B) False

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At what age should screening for colorectal cancer begin?


A) in the 20s
B) in the 30s
C) in the 40s
D) in the 50s
E) in the 60s

F) B) and E)
G) B) and D)

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A Pap test looks for what type of cancer?


A) skin cancer
B) esophageal cancer
C) bladder cancer
D) cervical cancer
E) colon cancer

F) A) and E)
G) A) and B)

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Hodgkin lymphomas develop from


A) cells of the liver and spleen.
B) all types of white blood cells.
C) B or T cells.
D) mutated B cells.
E) bladder epithelial cells.

F) A) and E)
G) A) and D)

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Which of the following is not a type of chemotherapy?


A) alkylating agents
B) antimetabolites
C) antitumor antibiotics
D) bone marrow transplants
E) mitotic inhibitors

F) A) and D)
G) None of the above

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List the characteristics of cancer cells that make them different from noncancer cells.

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1. Cancer cells lack differentiation.
2....

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What is the survival rate for children with childhood leukemia?


A) 10%
B) 30%
C) 50%
D) 80%
E) 99%

F) None of the above
G) B) and C)

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Contact inhibition means that


A) there are more chromosomes within the nucleus than there should be.
B) cells are able to divide without the presence of stimulatory growth factors.
C) cells only divide a certain specified number of times and then quit.
D) when cells come in contact with a neighbor, they stop dividing.
E) cells have gained the ability to invade lymphatic and blood vessels.

F) None of the above
G) A) and E)

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Which is responsible for more cancer deaths in women: breast, colon and rectum, pancreas, or ovary?


A) breast
B) colon and rectum
C) pancreas
D) ovary
E) all are equal

F) C) and E)
G) None of the above

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Which accounts for more cancer deaths in males: bladder, pancreas, esophagus, or prostate?


A) bladder
B) pancreas
C) esophagus
D) prostate
E) all are equal

F) A) and B)
G) A) and C)

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Which of the following is not a stage of carcinogenesis?


A) initiation
B) promotion
C) progression
D) differentiation
E) angiogenesis

F) B) and C)
G) A) and B)

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Which of the following is not one of the seven warning signs?


A) a cut that bleeds
B) change in bowel or bladder habits
C) thickening or lump in breast or elsewhere
D) indigestion or difficulty swallowing
E) obvious change in wart or mole

F) C) and D)
G) B) and E)

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Which of the following tests is not used to screen for colon cancer?


A) blood test
B) digital examination
C) flexible sigmoidoscopy
D) fecal occult blood test
E) double-contrast barium enema

F) All of the above
G) B) and E)

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Epstein-Barr virus is routinely isolated from cases of cervical cancers.

A) True
B) False

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Which of the following is not a protective behavior that will help prevent cancer?


A) Don't use tobacco.
B) Increase consumption of salt-cured, smoked, and nitrite-cured foods.
C) Don't sunbathe.
D) Avoid radiation.
E) Increase consumption of vegetables from the cabbage family.

F) C) and E)
G) C) and D)

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Which of the following is not a type of immunotherapy?


A) cancer vaccines
B) anti-p53 engineered adenovirus
C) cytokine therapy
D) monoclonal antibodies
E) genetically engineered antigen presenting cells

F) All of the above
G) A) and E)

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If you have one of the seven warning signals in CAUTION, this means that you have cancer.

A) True
B) False

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If you receive the new vaccine against HPV, then you do not need to get Pap tests anymore.

A) True
B) False

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